No regrets here. I have heard of some people who regretted it, but it was based on who they went with as their source of tuning the truck.
Some tuners make things a little too hot for our engine (or transmission and driveline parts even) to handle and things don't hold together. I can't say I've had any such problems with hACKmans Customs (Jason Hackler) who's tunes are sold by Shield & Spear Performance https://www.snsperformance.store/
Jason's tunes may not be the biggest out there as he has said before, but they are focused on being reliable, safe on your truck, good MPG's and also giving your truck better performance (it won't be a Corvette, or even like a tuned and deleted 6.6 Duramax, but it's a world of difference from a stock truck).
I opted to tune at 45k miles and say the heck with the warranty because I didn't want to deal with DEF anymore or worry about the DPF acting up. That and the EGR isn't putting nasty crap back into the engine anymore.