Short answer: no. Well, maybe. Aw heck, there is no short answer.
The key to getting tall tires under these is to run tall skinny tires like a 255/80 on a stock 17" wheel with factory 33mm offset. Anyway, read on.
As far as rubbing goes, You'd be borrowing from Paul to pay Peter
Wheel spacers are like having wider wheels, or negative offset. It's going to make your tires closer to the outer edges of the fender and the body near the front of the door. Instead of rubbing sway bar or frame, you'd be rubbing fender or body
To really see what would happen, you need a helper and a tape measure. Have the helper move the wheel to lock, hold it and measure all the clearances at the tire shoulder. Check clearance and the swaybar, and inner fenders, etc. Then do the other direction. While you're doing this, you have to visualize where the wheel spacers would push the tire out to and see if you have room. Wheel spacers also push the tire out away from the pivot fulcrum which makes it travel more when you steer, Go kart tire would be the best example I can think of because of the extreme negative offsets on their wheels, when you turn a go kart wheel the tire swings rather than pivoting, it has a long wide sweep.
My wheels (18x9 with 20mm offset) are 1" wider than the factory wheels (17x8 with 33mm offset) which is nearly identical to running a 1" wheel spacer. Anyway, I was stuck running a much smaller tire than some people have reported running because of my wheel. This is due to the tire now being closer to the outer fender.
I have 2" front/ 2" rear and my max tire size on my setup was 265/65/18 which is a small 32". I'm extremely close to rubbing, and I have rubbed on occasion whipping a U turn (full lock, body roll)
Also, keep in mind not all trucks measure out same, and some sit higher or lower than others etc.
Gm made it hard to fit big tires under these things. Heck, even the bds kit and maybe the rough country lift kits include weld on steering stops to run the max tire size without rubbing
Hope this helps